Lignans Angiogenesis

Eat Yourself to Healthy Living

Lignans are polyphenols (antioxidants) found in plants.
Antioxidants destroy Free Radicals which are groups or chains of unstable atoms that do damage to D.N.A. and can damage or neutralise healthy cells.

The principle anti-oxidants are Vitamin E, Vitamin C and Beta-Carotene.
Try adding small quantities of some of these foods into your daily Eating Habits :
Vitamin E: nuts, seeds, vegetables, fish oils, Tofu wholegrain, wheat germ and apricots
Vitamin C: citrus fruits, green peppers, cabbage, spinach, broccoli, Brussel sprouts, kiwi fruit & strawberries
Beta Carotene: liver, egg yolk, milk, butter, spinach, carrots, squash, broccoli, yams, tomatoes, peaches and grains.
Linseed Brown or Golden Both have very similar nutritional benefits,(these are better for you if you grind them),Linseed is the “World’s Number 1 source” of Plant Lignans, and is a complete protein which is rare for plant protein.Once eaten, Lignans are changed in the colon by gut bacteria into enterolignans (enterolactone and enterodiol).
NB: The main types of Plant Lignans are as follows:
Secoisolariciresinol – found in flax seed
Matairesinol & Pnioresinol- found in sesame seeds and to a lesser extent flax seed
Lariciresinol – found in small quantities in linseeds, sesame seeds and Brassica vegetables (cauliflower, kale, brussel sprouts, broccoli & cabbage).

Flax lignans may also reduce cancer risks by preventing pre-cancerous cellular changes by reducing angiogenesis(the formation of new small blood vessels) An example of this is where the skin is breached, due to a cut and these new blood vessels are formed to help the healing process.

However, it is now believed that this same process may also be responsible for feeding cancerous cells which enables them to grow. And anti- angiogenesis is an attempt to cut off the blood supply to the tumour, thereby reducing its size and potency and prevent metastasis ie. the spread of the cancer to other parts of the body. It is also believed to have the potential to decrease the incidence of several chronic diseases.
Angiogenesis: Have a look at Dr. William Li’s lecture on TED.com

Metastasis (METS)
Is the spread of cancer cells. Cancer cells differ in form depending on which organ is affected. Eg. Cancerous cells in the liver differ from those in the lung. However, when cancerous cells, which would normally be found in the liver, begin to appear in the lungs, this indicates that metastasis has occurred ie. The liver cancer has spread.
Linseed has not only huge amounts of lignans, but also fibre, phyto-chemicals, other nutrients with cardio-protective effects. It also contains alpha-linolenic acid (A.L.A.) and its associated health benefits

Enterolignans act as weak phytoestrogens which have the ability to induce phase 2 proteins.Below are some
foods that induce Phase 2 Proteins:- Gooseberries,Strawberries,Blueberries Rasberries,Blackberries,Cauliflower, Leeks, Sprouts to name but a few which inhibit the activity of certain enzymes. They also may protect against cardio-vascular disease by reducing lipid and glucose concentrations, lowering blood pressure and
decreasing oxidative stress and inflammation in the body.

Estrogens
Are signalling molecules, binding to estrogen receptors in the cells. Estrogen receptors interact with D.N.A., not only for reproduction purposes, but also for the health of bones, liver, heart and brain.

Phytoestrogens
Mimic estrogens and latch onto estrogen receptors in the cells. The effect of this is that these phytoestrogens take up space on these receptors which helps to prevent the overloading of estrogen in the cells at a time when they are not needed eg. post- reproduction years , which may reduce the risk of hormone induced cancers eg. breast, colon, uterine, ovarian and prostate cancers.

All plants have a glue-like substance called mucilage,(linseed has a great deal of this) which when ingested, prevents the stomach from emptying too quickly into the small intestine, thus allowing the body to take more goodness out of the food we eat.

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